Intrathoracic extramedullary haematopoiesis complicated by massive haemothorax in alpha-thalassaemia

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Intrathoracic extramedullary haematopoiesis complicated by massive haemothorax in alpha-thalassaemia.

Intrathoracic extramedullary haematopoiesis (EMH) is a rare entity that is usually asymptomatic. A 44 year old man with alpha-thalassaemia is described who developed dyspnoea and massive left sided haemothorax. The haemoglobin disorder was established by Hgb H staining and haemoglobin electrophoretic studies. The DNA analysis revealed it to be a case of double heterozygous terminal codon mutati...

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Case report Intrathoracic extramedullary haematopoiesis complicated by massive haemothorax in alpha-thalassaemia

Intrathoracic extramedullary haematopoiesis (EMH) is a rare entity that is usually asymptomatic. A 44 year old man with alpha-thalassaemia is described who developed dyspnoea and massive left sided haemothorax. The haemoglobin disorder was established by Hgb H staining and haemoglobin electrophoretic studies. The DNA analysis revealed it to be a case of double heterozygous terminal codon mutati...

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Extramedullary haematopoiesis presented as intrathoracic tumour in a patient with alpha-thalassaemia

The authors report a case of extramedullary haematopoiesis (EMH) presenting as an intrathoracic tumour in a patient with alpha-thalassaemia. CT scan and MRI of the chest were obtained and followed by tumour excision. Compared to beta-thalassaemia, only two cases of EMH in patients with alpha-thalassaemia have been described in the literature. A possible reason for this disparity is discussed.

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Spinal cord compression due to intrathoracic extramedullary haematopoiesis in homozygous thalassaemia.

A rare condition of massive intrathoracic extramedullary haematopoiesis causing spinal cord compression is presented in a 17-year-old Saudi male. Both clinical and laboratory findings, together with the computed tomographic evaluation of the lesion are described. Partial surgical resection as an alternative to radiotherapy has resulted in a dramatic response.

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Intrathoracic extramedullary hematopoiesis related spontaneous hemothorax.

A 39-year-old man had the history of b-thalassemia intermedia and had undergone splenectomy in his childhood. Intrathoracic extramedullary hematopoiesis (EMH) mass was noted on routine follow-up image (Figure 1a). One day, he suffered from acute onset of right upper back pain with dyspnea. He was then sent to our emergency department, and the chest plain film revealed massive right pleural effu...

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ژورنال

عنوان ژورنال: Thorax

سال: 1999

ISSN: 0040-6376

DOI: 10.1136/thx.54.5.466